Ultra-High Concentration Low-Viscosity Subcutaneous Antibody Formulations using Ionic Liquids. Ramesh A, Erdi M, Zang S, Chandra Suja V, Mitragotri S, Singh B. Journal of Controlled Release, 2025, 388, 114295.
2025
2024
Dual-Sensing Nanoreporter for Dynamic and High-Throughput Monitoring of Immune Checkpoint Inhibitor Responses in Tumor-Derived Organoids. Nguyen A, Ramesh A, Fish A, Kulkarni A. Advanced Functional Materials, 2024, 34, 2400393.
2023
Caspase-1 Responsive Nanoreporter for In Vivo Monitoring of Inflammasome Immunotherapy. Nandi D, Forster III J, Ramesh A, Nguyen A, Bharadwaj H, Kulkarni A, ACS Applied Materials & Interfaces, 2023, 15 (48), 55545-55558
Activatable Nanoreporters for Real-Time Tracking of Macrophage Phenotypic States Associated with Disease Progression. Ramesh A, Deshpande N, Malik V, Nguyen A, Malhotra M, Debnath M, Brouillard A, Kulkarni A. Small, 2023, 19, 2300978.
Nanoreporter for Real-Time Monitoring of Inflammasome Activity and Targeted Therapy. Nandi D, Forster III J, Ramesh A, Nguyen A, Bharadwaj H, Kulkarni A. Advanced Sciences. 2023, 10, 2204900.
Protein Corona Formation on Lipid Nanoparticles Negatively Affects the NLRP3 Inflammasome Activation. Debnath M, Forster III J, Ramesh A, Kulkarni A. Bioconjugate Chemistry, 2023 34 (10), 1766-1779
2022
Supramolecular nanotherapeutics enable metabolic reprogramming of tumor-associated macrophages to inhibit tumor growth. Ramesh A, Malik V, Brouillard A, Kulkarni A. J Biomed Mater Res. Part A, 2022, 110(8), 1448-1459.
Chapter Four—Delivery strategies for reprogramming tumor-associated macrophages. Ramesh A, & Kulkarni A. In M. M. Amiji & L. S. Milane (Eds.), Systemic Drug Delivery Strategies (pp. 83–115). Academic Press
2021
Rational combination of an immune checkpoint inhibitor with CSF1R inhibitor–loaded nanoparticle enhances anticancer efficacy. Ramesh A, Malik V, Ranjani H.A, Smith H, and Kulkarni A. Drug Deliv. and Transl. Res, 2021, 11, 2317-2327
TLR7/8 Agonist and SHP2 Inhibitor Loaded Nanoparticle Enhances Macrophage Immunotherapy Efficacy. Malik V, Ramesh A and Kulkarni A. Advanced Therapeutics, 2021, 4, 2100086
Supramolecular Nanotherapeutics for Macrophage Immunotherapy. Ramesh A, Brouillard A, Kulkarni A. ACS Applied Bio Materials. 2021,4 (6), 4653-4666
2020
Granzyme B nanoreporter for early monitoring of tumor response to immunotherapy. Nguyen A, Ramesh A, Kumar S, Nandi D, Brouillard A, Wells A, Pobezinsky L, Osborne B, and Kulkarni A. Science Advances, 2020, 6, eabc2777.
A Nitric Oxide (NO) Nanoreporter for Noninvasive Real-Time Imaging of Macrophage Immunotherapy. Ramesh A, Kumar S, Brouillard A, Nandi D, Kulkarni A. Advanced Materials. 2020, 32, 2000648.
Supramolecular Polysaccharide Nanotheranostics that Inhibit Cancer Cells Growth and Monitor Targeted Therapy Response. Deshpande N, Ramesh A, Nandi D, Nguyen A, Brouillard A, Kulkarni A. Nanotheranostics. 2020 May 18; 4(3):156-172.
Targeting macrophages: a novel avenue for cancer drug discovery. Kumar S, Ramesh A, Kulkarni A. Expert Opinion on Drug Discovery, 2020, 15(5), 561–574.
Lipid-based phagocytosis nanoenhancer for macrophage immunotherapy. Ramesh A, Kumar S, Nguyen A, Brouillard A, Kulkarni A. Nanoscale, 2020, 12, 1875–1885
Dual inhibition of CSF1R and MAPK pathways using supramolecular nanoparticles enhances macrophage immunotherapy. Ramesh A, Brouillard A, Kumar S, Nandi D, Kulkarni A. Biomaterials, 2020, 227, 119559.
2019
CSF1R- and SHP2-Inhibitor-Loaded Nanoparticles Enhance Cytotoxic Activity and Phagocytosis in Tumor-Associated Macrophages. Ramesh A, Kumar S, Nandi D, Kulkarni. Advanced Materials, 2019, 31, 1904364.
Dual Inhibitors-Loaded Nanotherapeutics that Target Kinase Signaling Pathways Synergize with Immune Checkpoint Inhibitor. Ramesh A, Natarajan S.K, Nandi D, Kulkarni A. Cel. Mol. Bioeng, 2019.12, 357–373
A designer self-assembled supramolecule amplifies macrophage immune responses against aggressive cancer Kulkarni A, Chandrasekar V, Natarajan S.K, Ramesh A, Pandey P, Nirgud J, Bhatnagar H, Ashok D, Ajay, A.K, and Sengupta S. Nature Biomedical Engineering, 2018, 2, 589–599.